Réaction #502148
ord-3a2af563e55642549d5e7367ca025bfe
Équation de réaction
2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
4,4-dimethylpiperidine
→
title compound
4-(4,4-Dimethylpiperidin-1-yl)-2-(3-chlorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Réactifs
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
In analogy to the preparation of Example 1, 150 mg (0.51 mmol) of 2-(3-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 582 mg (5.14 mmol) of 4,4-dimethylpiperidine to give 96 mg (52% of theory) of the title compound.