Réaction #5014

Équation de réaction

1-(4-aminobutyl)-4-(2-pyrimidinyl)piperazine

3-oxabicyclo[3.2.1]octan-2,4-dione

→

title compound

Rendement 34.0%

3-(4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl)-3-azabicyclo[3.2.1]octan-2,4-dione

Rendement 34.0%

Conditions de réaction

Mode opératoire

The title compound was prepared from 1.92 g (8.2 mmol) of 1-(4-aminobutyl)-4-(2-pyrimidinyl)piperazine and 1.14 g (8.14 mmol) of 3-oxabicyclo[3.2.1]octan-2,4-dione, substantially following the procedure of Example 1. Yield: 1.0 g (34% yield).

Source