Réaction #5007

ord-9bbd528effc4400bb7abc75186c3da13

Équation de réaction

Cc1ccccc1CBr
2-methylbenzyl bromide
CC(C)OP(OC(C)C)OC(C)C
triisopropyl phosphite
→
Cc1ccccc1CP(=O)(OC(C)C)OC(C)C
diisopropyl 2-methylbenzylphosphonate

Réactifs

Cc1ccccc1CBr
2-methylbenzyl bromide
CC(C)OP(OC(C)C)OC(C)C
triisopropyl phosphite

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    workup.DISTILLATIONDuring this procedure, i-propyl bromide distilled off
  2. 2
    workup.DISTILLATIONThe product was distilled through a 30 cm Vigreux column

Mode opératoire

34.5 g (0.19 mol) of 2-methylbenzyl bromide and 39 g (0.19 mol) of triisopropyl phosphite were heated at 150° C. for 2 hours. During this procedure, i-propyl bromide distilled off. The product was distilled through a 30 cm Vigreux column.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05242908uspto-grants-1993_09