Réaction #49018

ord-a883d400e1b046fa919b9cf815c9e993

Équation de réaction

COC(=O)CON1C(=O)c2ccccc2C1=O
(1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-acetic acid methyl ester
CC(C)N
isopropylamine
CC(C)NC(=O)CON
2-aminooxy-N-isopropyl-acetamide

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Using (1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-acetic acid methyl ester obtained in Step A of Example 19 and isopropylamine as an amine, synthesis was performed according to the procedure described in Step A of Example 20 to give 2-aminooxy-N-isopropyl-acetamide.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07745663B2uspto-grants-2010_06