Réaction #484303

Équation de réaction

methyl 3-amino-2-[[(2′-cyanobiphenyl-4-yl)methyl]amino]benzoate

2,2,2-trifluoroethyl orthocarbonate

→

title compound

Rendement 25.0%

Methyl 1-[(2′-cyanobiphenyl-4-yl)methyl]-2-(2,2,2-trifluoroethoxy)benzimidazole-7-carboxylate

Rendement 25.0%

Conditions de réaction

Mode opératoire

The title compound was prepared as pale yellow crystals from methyl 3-amino-2-[[(2′-cyanobiphenyl-4-yl)methyl]amino]benzoate and 2,2,2-trifluoroethyl orthocarbonate according to the procedure for Working Example 3. Yield: 25%, m.p. 143-145° C.

Source