Réaction #47736
ord-b51d7cb6b41e41718e3f39d76b7da4bc
Équation de réaction
Glutaric anhydride
3-ethynylaniline
→
product
Rendement 99.0%
4-(3-Ethynyl-phenylcarbamoyl)-butyric acid
Rendement 99.0%
Réactifs
Aucun
Solvants
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Traitement
- 1Autrewas evaporated under reduced pressure
Mode opératoire
Glutaric anhydride (215 mg, 1.9 mmol) was dissolved in anhydrous dichloromethane (7 ml) and followed by the addition of 3-ethynylaniline (200 mg, 1.7 mmol). The mixture was allowed to stir at room temperature for 6 hours before the solvent was evaporated under reduced pressure to provide the product as a white solid (363 mg, 99%);