Réaction #4690

Équation de réaction

isopropyl ether

hydrogen chloride

product

3,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole

→

3,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole hydrochloride

Solvants

ethanol

ethanol

Conditions de réaction

Traitement

1. 1
   workup.STIRRINGThe mixture was stirred for 24 hours
2. 2
   Filtrationwas filtered
3. 3
   Filtrationfiltered
4. 4
   Autredried under pressure

Mode opératoire

2.9 ml of a solution of 5.9N hydrogen chloride in ethanol were aded to a solution of 5 g of the product of Example 1 in 5 ml of ethanol and the mixture was stirred while adding isopropyl ether thereto. The mixture was stirred for 24 hours and was filtered. The product was empasted with isopropyl ether, filtered and dried under pressure to obtain 4.4 g of 3,4-bis-(4-methoxyphenyl)-5-ethyl-4H-1,2,4-triazole hydrochloride.

Source