Réaction #46712

ord-42b9c346e4594c3b87f17142402350a2

Équation de réaction

CC(C)S(=O)(=O)NC1Cc2ccc(I)cc2C1
N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide
CN(C)S(=O)(=O)c1cccc(B(O)O)c1
{3-[(dimethylamino)sulfonyl]phenyl}boronic acid
→
CC(C)S(O)(O)NC1Cc2ccc(-c3cccc(S(=O)(=O)N(C)C)c3)cc2C1
title compound
CC(C)S(O)(O)NC1Cc2ccc(-c3cccc(S(=O)(=O)N(C)C)c3)cc2C1
3-(2-{[dihydroxy(1-methylethyl)-λ4-sulfanyl]amino}-2,3-dihydro-1H-inden-5-yl)-N,N-dimethylbenzenesulfonamide

Réactifs

CC(C)S(=O)(=O)NC1Cc2ccc(I)cc2C1
N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide
CN(C)S(=O)(=O)c1cccc(B(O)O)c1
{3-[(dimethylamino)sulfonyl]phenyl}boronic acid

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The title compound was prepared from N-(5-iodo-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide and {3-[(dimethylamino)sulfonyl]phenyl}boronic acid (WO2003004472) in a similar manner to Example 1.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07741351B2uspto-grants-2010_06