Réaction #457144

Équation de réaction

2-Nitro-6,6a,7,8,9,10-hexahydro-12H-pyrido[2,1-c][1,4]benzoxazepine hydrochloride

→

solid

Rendement 103.6%

2-Amino-6,6a,7,8,9,10-hexahydro-12H-pyrido[2,1-c][1,4]benzoxazepine hydrochloride

Rendement 103.6%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   Filtrationfiltered
2. 2
   Autreevaporated

Mode opératoire

2-Nitro-6,6a,7,8,9,10-hexahydro-12H-pyrido[2,1-c][1,4]benzoxazepine hydrochloride (2.46 g) dissolved in methanol (50 ml) was treated with 10% Pd-C (0.25 g), and hydrogenated on a Parr Hydrogenator for one hour, filtered and evaporated to yield a tacky solid (2.28 g).

Source