Réaction #456888

Équation de réaction

4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine

1,2,3,4-tetrahydroquinoline

→

4-(1,2,3,4-Tetrahydroquinolin-1-yl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine

Solvants

toluene acetone

Conditions de réaction

Traitement

1. 1
   AutreThis product is prepared in a manner analogous to

Mode opératoire

This product is prepared in a manner analogous to that described in Example 1 from 4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine and 1,2,3,4-tetrahydroquinoline (4 equivalents, Fluka, Buchs, Switzerland). M.p: 263-264° C.; FAB-MS: (M+H)+ =279 (corresponds to C17H18N4); Rf value (toluene-acetone--(4:6))=0.29.

Source