Réaction #452416

Équation de réaction

n-heptyl bromide

NaHCO3

m-aminophenol

→

3-(n-heptyl-amino)phenol

Rendement 62.0%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   Températurethe mixture is refluxed for 5 h
2. 2
   TempératureAfter cooling
3. 3
   Filtrationit is filtered
4. 4
   Autrethe solvent is removed in vacuo

Mode opératoire

0.11 mol of n-heptyl bromide and 0.1 mol of NaHCO3 are added to 0.1 mol of m-aminophenol in 150 ml of methanol, and the mixture is refluxed for 5 h. After cooling, it is filtered and the solvent is removed in vacuo. The oil which remains is fractionated in vacuo, to give 3-(n-heptyl-amino)phenol.

Source