Réaction #44352

Équation de réaction

Morpholine

4-bromo-2,5-difluoro-benzenesulfonyl chloride

→

sub-title compound

4-[(4-bromo-2,5-difluorophenyl)sulfonyl]-morpholine

Solvants

dichloromethane

Conditions de réaction

Traitement

1. 1
   Autrequenched with water
2. 2
   SéchageThe organic phase was dried (MgSO4)
3. 3
   Concentrationconcentrated in vacuo

Mode opératoire

Morpholine (0.16 ml) was added to a stirred solution of 4-bromo-2,5-difluoro-benzenesulfonyl chloride (0.18 g) in dichloromethane (6 ml) under nitrogen. The reaction mixture was stirred overnight and then quenched with water. The organic phase was dried (MgSO4) and concentrated in vacuo to give the sub-title compound as a white solid (200 mg).

Source