Réaction #43703

Équation de réaction

3-bromo-2-fluorobenzaldehyde

sodium hydride

methyl mercaptoacetate

→

title compound

Methyl7-bromo-1-benzothiophene-2-carboxylate

Conditions de réaction

Mode opératoire

Using 27.8 g (137.1 mmol) of 3-bromo-2-fluorobenzaldehyde, 8.2 g (205.7 mmol) of sodium hydride (60% pure) and 16.0 g (150.9 mmol) of methyl mercaptoacetate, 20.57 g of a mixture of the title compound and the corresponding acid (about 1:1) are obtained.

Source