Réaction #433284

Équation de réaction

ethylene

1-bromo-3,5-dimethyl adamantane

1-Bromo-3,5-dimethyl Adamantane

aluminum bromide

→

1-(2-Bromoethyl)-3,5-dimethyl Adamantane

Rendement 48.0%

Solvants

hexane

Conditions de réaction

Traitement

1. 1
   Autrefor 20-30 minutes
2. 2
   workup.ADDITIONpour the reaction mixture onto ice water
3. 3
   ExtractionExtract with ether
4. 4
   Autredry the organic phase
5. 5
   Autreevaporate to dryness
6. 6
   AutreRecrystallize the residue from methanol

Mode opératoire

Mix 1.4 mol of 1-bromo-3,5-dimethyl adamantane (I) in hexane with 0.6 mol of aluminum bromide at -75° C. Subsequently, pass ethylene through the solution for 20-30 minutes, stir for 5 min., and pour the reaction mixture onto ice water. Extract with ether, dry the organic phase and evaporate to dryness. Recrystallize the residue from methanol. (Yield: 48%).

Source