Réaction #431314

ord-32fedbddc3704edc882f4ca0f7cc5f0e

Équation de réaction

COc1cc2nc(CCC(C)C)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2cc1OC
tert.butyl 4'-[(2-(3-methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid
→
COc1cc2nc(CCC(C)C)n(Cc3ccc(-c4ccccc4C(=O)O)cc3)c2cc1OC
4'-[(2-(3-Methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

Réactifs

COc1cc2nc(CCC(C)C)n(Cc3ccc(-c4ccccc4C(=O)OC(C)(C)C)cc3)c2cc1OC
tert.butyl 4'-[(2-(3-methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid

Réactifs

Aucun

Solvants

ClCCl
methylene chloride

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-(3-methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05864043uspto-grants-1999_01