Réaction #431312

ord-6662557d8aa84da89012ab88852009af

Équation de réaction

CCCCc1nc2cc(OC)c(OC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1
tert.butyl 4'-[(2-n-butyl-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid
→
CCCCc1nc2cc(OC)c(OC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1
4'-[(2-n-Butyl-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

Réactifs

CCCCc1nc2cc(OC)c(OC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1
tert.butyl 4'-[(2-n-butyl-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate
O=C(O)C(F)(F)F
trifluoroacetic acid

Réactifs

Aucun

Solvants

ClCCl
methylene chloride

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05864043uspto-grants-1999_01