Réaction #42728

Équation de réaction

4-iodophenylacetic acid

hydrochloric acid

MeOH

→

title compound

Rendement 98.0%

Methyl 4-Iodophenylacetate

Rendement 98.0%

Solvants

dioxane

Conditions de réaction

Traitement

1. 1
   Autrethe solvent was removed under reduced pressure

Mode opératoire

To a stirred solution of 4-iodophenylacetic acid (5.0 g, 19.1 mmol) in MeOH (200 mL) was added 4N hydrochloric acid in dioxane (10 mL). The reaction mixture was stirred for 24 h at room temperature and then the solvent was removed under reduced pressure to give the title compound (5.17 g, 98% yield), which was used without further purification.

Source