Réaction #41987

ord-736cdd0e368242faa9ac6b54fa0a8699

Équation de réaction

CCC1(O)CCc2cc(F)ccc21
1-ethyl-5-fluoro-indan-1-ol
COC(=O)c1cccc2cc[nH]c12
1H-indole-7-carboxylic acid methyl ester
→
CCC1(c2c[nH]c3c(C(=O)OC)cccc23)CCc2cc(F)ccc21
title compound
CCC1(c2c[nH]c3c(C(=O)OC)cccc23)CCc2cc(F)ccc21
3-(1-Ethyl-5-fluoro-indan-1-yl)-1H-indole-7-carboxylic acid methyl ester

Réactifs

CCC1(O)CCc2cc(F)ccc21
1-ethyl-5-fluoro-indan-1-ol
COC(=O)c1cccc2cc[nH]c12
1H-indole-7-carboxylic acid methyl ester

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 1H-indole-7-carboxylic acid methyl ester, the title compound is prepared as in example 1. 103 mg (75%). LC-MS m/z 338.1 (M++1).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07728150B2uspto-grants-2010_06