Réaction #417967

Équation de réaction

17a

N-(4-chloro-3-hydroxyphenyl)acetamide

cesium carbonate

4-(2-chloroethyl) morpholine hydrochloride

→

compound 23a

Rendement 69.0%

N-[4-chloro-3-(2-morpholin-4-yl-ethoxy)-phenyl]-acetamide

Rendement 69.0%

Conditions de réaction

Mode opératoire

The compound 23a was prepared by using the general procedure H, as given in Example 9, in 69% yield starting from 17a, with 2.5 eq of cesium carbonate and 1.1 eq of 4-(2-chloroethyl) morpholine hydrochloride.

Source