Réaction #417926

Équation de réaction

sodium hydroxide

33

methyl 4-(undec-4Z-enyloxy)benzoate

→

white solid

Rendement 98.1%

4-(undec-4Z-enyloxy)benzoic acid

Rendement 98.1%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   TempératureThe solution is refluxed for 20 hours
2. 2
   AutreAfter evaporating off the solvent
3. 3
   Extractionextracted with DCM

Mode opératoire

550 μL of 1 N sodium hydroxide solution (550 μmol) are added portionwise to 109 mg of 33 (358 μmol) in methanol (4 mL). The solution is refluxed for 20 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 102 mg of a white solid are obtained, i.e. a yield of 98%.

Source