Réaction #4069

Équation de réaction

N-bromosuccinimide

methyl phenylacetate

→

title compound

Rendement 93.1%

Methyl Bromo-Phenylacetate

Rendement 93.1%

Solvants

carbon tetrachloride

Conditions de réaction

Traitement

1. 1
   Températureto reflux
2. 2
   Températurerefluxed for about 12 hours
3. 3
   Filtrationfiltered
4. 4
   ConcentrationThe filtrate was concentrated by evaporation under vacuum

Mode opératoire

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

Source