Réaction #4031

Équation de réaction

Methyl perfluorobutyrate

sodium trimethylsilanolate

→

sodium perfluorobutyrate

Rendement 84.0%

Solvants

ether

Conditions de réaction

Traitement

1. 1
   FiltrationThe solid was filtered under nitrogen
2. 2
   Lavagewashed with dry ether
3. 3
   Autredried under a stream of nitrogen

Mode opératoire

Methyl perfluorobutyrate (12.81 g, 56 mmol) was added dropwise to a stirred solution of sodium trimethylsilanolate (6.3 g, 56 mmol) in dry ether (300 mL) at room temperature under nitrogen. The reaction mixture was stirred overnight. The solid was filtered under nitrogen, washed with dry ether, and dried under a stream of nitrogen to afford sodium perfluorobutyrate (11.1 g, 84% yield) as a white solid: 19F NMR (D2O) δ -79.6 (t, J=8 Hz, CF3 --, 3F), -117.2 (q, J=8 Hz, CF3CF2CF2 --, 2F), -126.2 ppm (s, CF3CF2 --, 2F). Anal. Calcd. for C4F7NaO2 : C, 20.36; F, 56.35; Na, 9.74. Found: C, 20.84, 20.61, 20.58; F, 56.68, 53.24; Na, 9.89, 9.65.

Source