Réaction #3960

Équation de réaction

8-(2-dimethylamino-4-nitro-phenyl)purin-6-one

hydrogen

→

8-(4-Amino-2-dimethylamino-phenyl)-purin-6-one

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   FiltrationAfter the catalyst has been subjected to suction filtration
2. 2
   Autrethe filtrate is evaporated to dryness in vacuo

Mode opératoire

An amount of 0.9 gm of 8-(2-dimethylamino-4-nitro-phenyl)purin-6-one is hydrogenated in 50 ml of methanol in the presence of 0.5 gm of Raney nickel at ambient temperature and under 5 bars of pressure with hydrogen for three hours until the calculated quantity has been taken up. After the catalyst has been subjected to suction filtration, the filtrate is evaporated to dryness in vacuo.

Source