Réaction #367273

Équation de réaction

6-chloro-1-hexanol

mercaptoacetic acid

→

6-(Carboxymethylthio)-1-hexanol

Solvants

NaOH

Conditions de réaction

Traitement

1. 1
   Extractionextracted repeatedly with ethyl acetate
2. 2
   ConcentrationThe combined extracts are concentrated to dryness
3. 3
   Autrethe residue purified by recrystallization

Mode opératoire

4.5 ml (0.04M) of 6-chloro-1-hexanol is added to a solution of 2.8 ml (0.04M) of mercaptoacetic acid in 120 ml of 1N NaOH. The solution is warmed to about 50° C. for 16 hours, then acidified and extracted repeatedly with ethyl acetate. The combined extracts are concentrated to dryness and the residue purified by recrystallization.

Source