Réaction #352819

ord-0597742d06cf4b7aab92ee2fd1c449ff

Équation de réaction

CC(=O)C(Cl)CCCl
3,5-dichloro-2-pentanone
N#C[S-].[Na+]
sodium rhodanide
CC(=O)C(CCCl)SC#N
3-thiocyanato-5-chloro-2-pentanone
Rendement 96.3%

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

A solution of 155.5 g (1 mole) of 3,5-dichloro-2-pentanone with 83 g (1.024 moles) of sodium rhodanide in 1 litre of methyl-ethyl-ketone is boiled for 1 hour under stirring. Then the procedure described in Example 1 is followed. 171 g (96.2%) of 3-thiocyanato-5-chloro-2-pentanone are obtained, which after distillation identical in all respect with the product of Example 1.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05648498uspto-grants-1997_07