Réaction #351232

Équation de réaction

tetrazole

5-Cyanocyclopentyl tetrazole

triethylamine

1-bromo dodecane

→

5-Cyanocyclopentyl-2-dodecyl-2H-tetrazole

Solvants

acetonitrile

Conditions de réaction

Traitement

1. 1
   TempératureThe solution was heated
2. 2
   Températureto reflux

Mode opératoire

The tetrazole (b) obtained above (11.0 g; 0.067 moles) was dissolved in acetonitrile (150 mL) containing one equivalent of triethylamine (6.8 g; 0.067 moles). The solution was heated to reflux followed by the addition of 1-bromo dodecane (16.8 g; 0.067 moles). Isolation of the 2-isomer was achieved employing the same conditions described for Example 11.

Source