Réaction #348014

Équation de réaction

indole-3-carboxylic acid

1-bromononane

potassium carbonate

→

nonyl indole-3-carboxylate

Solvants

N,N-dimethylformamide

Conditions de réaction

Traitement

1. 1
   FiltrationAfter insoluble materials were filtered off
2. 2
   workup.ADDITIONthe filtrate was diluted with ethyl acetate
3. 3
   Lavagewashed with water and brine
4. 4
   Séchagedried over magnesium sulfate
5. 5
   Concentrationconcentrated
6. 6
   AutreThe solid was collected
7. 7
   Lavagewashed with hexane

Mode opératoire

A mixture of indole-3-carboxylic acid, 1-bromononane and potassium carbonate in N,N-dimethylformamide was stirred at room temperature for 15 hours. After insoluble materials were filtered off, the filtrate was diluted with ethyl acetate, washed with water and brine, dried over magnesium sulfate and concentrated. The solid was collected and washed with hexane to give nonyl indole-3-carboxylate.

Source