Réaction #343052

ord-ace6689b51774ea4845b266b7e04c7b7

Équation de réaction

CCCCCCCCCCCCCCCCCCN
octadecylamine
O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
D-glucose
→
CCCCCCCCCCCCCCCCCCNC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
N-Octadecyl-D-glucopyranosylamine

Réactifs

CCCCCCCCCCCCCCCCCCN
octadecylamine
O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
D-glucose

Réactifs

Aucun

Solvants

CCO
ethanol

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Températurethe solution is warmed to 70°
  2. 2
    AutreAfter a clear solution has formed
  3. 3
    TempératureThe mixture is cooled to 10°
  4. 4
    workup.WAITleft
  5. 5
    workup.WAITto stand for 15 minutes
  6. 6
    AutreThe crystal sludge formed
  7. 7
    Filtrationis filtered off with suction
  8. 8
    Lavagewashed twice with ethanol
  9. 9
    Autredried in vacuo

Mode opératoire

20 g of octadecylamine are dissolved in 120 ml of ethanol and the solution is warmed to 70°. 11 g of anhydrous D-glucose are added. After a clear solution has formed, stirring is continued at 70° for a further 15 minutes. The mixture is cooled to 10° and left to stand for 15 minutes. The crystal sludge formed is filtered off with suction, washed twice with ethanol and dried in vacuo.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04699899uspto-grants-1987_10