Réaction #339549

Équation de réaction

acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester

diethyl ether pentane

→

title compound

4-(4-Methoxy-butyl)-pyridin-3-ol

Solvants

acetic acid

Conditions de réaction

Traitement

1. 1
   TempératureAfter cooling
2. 2
   Filtrationthe precipitate is collected by filtration

Mode opératoire

A mixture of 39 mmol acetic acid 4-(4-methoxy-butyl)-pyridin-3-yl ester in 20 ml acetic acid is heated to 70° C. for 30 minutes. After cooling, 75 ml of diethyl ether/pentane (1:5) is added and the precipitate is collected by filtration. The title compound is obtained from the solid by re-crystallization from toluene and identified based on its Rf value.

Source