Réaction #334906

Équation de réaction

3-phenoxybenzyl acetate

sodium hydroxide

→

3-phenoxybenzyl alcohol

Rendement 95.0%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   workup.DISTILLATIONThen the methanol is distilled off
2. 2
   workup.DISSOLUTIONthe organic phase is dissolved in 30 cm3
3. 3
   Lavageof methylene chloride, washed with 10 cm3

Mode opératoire

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N sodium hydroxide solution are refluxed for three hours. Then the methanol is distilled off and the organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of 1N hydrochloric acid solution and 10 cm3. of water. 1.90 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 95%.

Source