Réaction #329947

Équation de réaction

NaOH

benzo[1,2-b:4,5-b′]dithiophene-4,8-dione

octyl p-toluenesulfonate

→

title compound

Rendement 62.0%

4,8-Dioctoxybenzo[1,2-b:4,5-b′]dithiophene

Rendement 62.0%

Solvants

ethanol

Conditions de réaction

Traitement

1. 1
   Températurethe mixture was refluxed for 1 h
2. 2
   FiltrationThe resulting precipitate was filtered
3. 3
   workup.ADDITIONthe filtrate was diluted with 100 mL water
4. 4
   Extractionextracted with 100 mL chloroform
5. 5
   ExtractionThe organic extraction
6. 6
   Séchagewas dried with anhydrous sodium sulfate
7. 7
   Autreevaporated in vacuo

Mode opératoire

1.0 g (4.5 mmol) of benzo[1,2-b:4,5-b′]dithiophene-4,8-dione was mixed with 0.65 g (10 mmol) of zinc dust in a flask. Then, 4 ml of ethanol and 15 ml of 20% NaOH was added and the mixture was refluxed for 1 h. 4.3 mL octyl p-toluenesulfonate was added in portions with stirring until the color changed to red. The resulting precipitate was filtered, the filtrate was diluted with 100 mL water and extracted with 100 mL chloroform. The organic extraction was dried with anhydrous sodium sulfate and evaporated in vacuo. Column chromatography on silica gel using dichloromethane and hexanes mixed solvents yielded the pure title compound as a white solid (1.24 g, 62%). 1HNMR (CDCl3): δ0.88-0.91 (6H, t, J=7 Hz), 1.31-1.38 (16H, m), 1.54-1.58 (4H, m), 1.84-1.89 (4H, m), 4.26-4.29 (4H, J=7 Hz), 7.36-7.37 (2H, d, J=6 Hz), 7.47-7.48 (2H, d, J=6 Hz).

Source