Réaction #3281

ord-d04022b22bcd4100a137a9c7f735c157

Équation de réaction

CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1
6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one
CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1
6-(2,6-Dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one
CC(C)N
isopropylamine
CC(C)Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1
6-(2,6-Dichlorophenyl)-2-isopropylamino-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThis compound was prepared by a procedure similar to

Mode opératoire

This compound was prepared by a procedure similar to that described in Example 40 starting with 6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one of Example 37 and isopropylamine; mp 194°-196° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05733914uspto-grants-1998_03