Réaction #3247

Équation de réaction

1,2-dihydro-4-phenyl-7-methyl-2-oxo-3-quinoline carboxylic acid ethyl ester

→

title compound

3-methyl-5H-indeno[2,1-c]quinoline-6,7-dion

Solvants

sulfuric acid

Conditions de réaction

Traitement

1. 1
   Autreto obtain a crystal
2. 2
   Autreprecipitated by filtration
3. 3
   AutreThe crystal obtained
4. 4
   Lavagewas washed with water and methanol in this sequence
5. 5
   Autreto give 1.5 g (

Mode opératoire

A mixture of 1,2-dihydro-4-phenyl-7-methyl-2-oxo-3-quinoline carboxylic acid ethyl ester (2.5 g, 8.1 mmol) and conc. sulfuric acid (20 ml) was stirred with heat at 95° C. for 10 hours. The reaction mixture was poured into ice water to obtain a crystal precipitated by filtration. The crystal obtained was washed with water and methanol in this sequence to give 1.5 g (yield 70.6 of the title compound.

Source