Réaction #317954

ord-b469d348c1e04250a5471fd0753fe8d4

Équation de réaction

Cl.ClCc1ccccn1
2-Chloromethylpyridine hydrochloride
CCOC(=O)c1ccc(O)cc1
ethyl 4-hydroxybenzenecarboxylate
CCOC(=O)c1ccc(OCc2ccccn2)cc1
compound
Rendement 83.7%
CCOC(=O)c1ccc(OCc2ccccn2)cc1
Ethyl 4-(pyridin-2-ylmethoxy)benzenecarboxylate
Rendement 83.7%

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

2-Chloromethylpyridine hydrochloride (500 mg) and ethyl 4-hydroxybenzenecarboxylate (506 mg) were processed in the same manner as in Production Example 1-1 to obtain the entitled compound (656 mg).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07566781B2uspto-grants-2009_07