Réaction #3121

Équation de réaction

4-hydroxybenzaldehyde

1,3-dibromopropane

→

product

Rendement 76.0%

1,3-bis(4-formyl-phenoxy)propane

Rendement 76.0%

Solvants

potassium carbonate

DMF

Conditions de réaction

Traitement

1. 1
   Températureunder reflux
2. 2
   workup.ADDITIONThe reaction mixture was poured
3. 3
   workup.DISTILLATIONinto cold distilled water
4. 4
   Autreto obtain a precipitate
5. 5
   FiltrationAfter filtration and vacuum
6. 6
   Autredrying the precipitate
7. 7
   Autrethe resultant was recrystallized in ethanol
8. 8
   Autreto obtain the white product (XII-1)

Mode opératoire

10.0 g of 4-hydroxybenzaldehyde and 8.3 g of 1,3-dibromopropane were reacted for 24 hours in 6.2 g of potassium carbonate solution in 100 ml of DMF under reflux. The reaction mixture was poured into cold distilled water to obtain a precipitate. After filtration and vacuum drying the precipitate, the resultant was recrystallized in ethanol to obtain the white product (XII-1). The product yield was 76%.

Source