Réaction #3066

Équation de réaction

ethyl 3-bromo-4-methylbenzoate

NBS

benzoyl peroxide

→

ethyl 3-bromo-4-bromomethylbenzoate

Solvants

CCl4

Conditions de réaction

Traitement

1. 1
   Températurewas refluxed for 4 h
2. 2
   Filtrationprocessed by filtration and chromatography

Mode opératoire

A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.

Source