Réaction #2805

Équation de réaction

1-chloromethyl-2-vinyl-benzene

sodium iodide

water

→

title compound

Rendement 95.0%

1-Iodomethyl-2-vinyl-benzene

Rendement 95.0%

Solvants

acetone

Conditions de réaction

Traitement

1. 1
   TempératureHeat
2. 2
   Températureat gentle reflux for 30 minutes
3. 3
   TempératureCool
4. 4
   Extractionextract with pentane (200 mL)
5. 5
   SéchageDry (MgSO4)
6. 6
   Autreevaporate the solvent in vacuo

Mode opératoire

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

Source