Réaction #2510

ord-bcfcdbed56674c439cbfcd16edd11134

Équation de réaction

COc1ccccc1N
o-anisidine
O=C(O)c1ccc(S(=O)(=O)Cl)cc1
4-(chlorosulfonyl)benzoic acid
→
COc1ccccc1NS(=O)(=O)c1ccc(C(=O)O)cc1
title compound
Rendement 95.7%
COc1ccccc1NS(=O)(=O)c1ccc(C(=O)O)cc1
4-[(2-Methoxyanilino)sulfonyl]benzoic acid
Rendement 95.7%

Réactifs

COc1ccccc1N
o-anisidine
O=C(O)c1ccc(S(=O)(=O)Cl)cc1
4-(chlorosulfonyl)benzoic acid

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Using o-anisidine (0.585 ml, 5.0 mmol) and 4-(chlorosulfonyl)benzoic acid (1.15 g, 5.0 mmol), the procedure of Reference Example 2 was repeated to obtain 1.47 g (95.5%) of the title compound in the form of pink powder.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05728835uspto-grants-1998_03