Réaction #2467956
ord-23186eaa44664f94a98b0e02aae92654
Équation de réaction
methyl 3-aminothiophene-2-carboxylate
sodium nitrite
dimethylamine
→
methyl 3-[(dimethylamino)diazenyl]thiophene-2-carboxylate
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
Diazotization of methyl 3-aminothiophene-2-carboxylate or its precursors with sodium nitrite followed by treatment with dimethylamine provides methyl 3-[(dimethylamino)diazenyl]thiophene-2-carboxylate or its derivatives in good yield. Treatment of the above esters with ammonia gave the triazene analogs of formula (I) (3-[(dimethylamino)diazenyl]thiophene-2-carboxamide (compd No. 1), compd. No. 2, compd. No. 3, compd. No. 4, compd. No. 5).