Réaction #2461614

Équation de réaction

4-amino-5-chloro-2,3-methylenedioxypyridine

2,3-methylenedioxypyridine

carbon dioxide

→

2,3-methylenedioxypyridine-4-carboxylic acid

Rendement 80.0%

Conditions de réaction

Mode opératoire

Using an analogous procedure to that described in the second paragraph of the portion of Example 1 that is concerned with the preparation of the starting material 4-amino-5-chloro-2,3-methylenedioxypyridine, 2,3-methylenedioxypyridine was reacted with carbon dioxide gas to give 2,3-methylenedioxypyridine-4-carboxylic acid in 80% yield; NMR Spectrum: (DMSOd6) 6.24 (s, 2H), 7.13 (d, 1H); 7.63 (d, 1H).

Source