Réaction #2461612

Équation de réaction

4-chloro-7-(3-chloropropoxy)quinazoline

4-amino-5-chloro-2,3-methylenedioxypyridine

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title compound

Rendement 89.0%

4-(5-chloro-2,3-methylenedioxypyrid-4-ylamino)-7-(3-chloropropoxy)quinazoline

Rendement 89.0%

Conditions de réaction

Mode opératoire

Using an analogous procedure to that described in Example 1, 4-chloro-7-(3-chloropropoxy)quinazoline was reacted with 4-amino-5-chloro-2,3-methylenedioxypyridine to give the title compound in 89% yield; NMR Spectrum: (DMSOd6 and CF3CO2D) 2.25 (m, 2H), 3.8 (t, 2H), 4.35 (t, 2H), 6.25 (s, 2H), 7.35 (s, 1H), 7.6 (d, 1H), 7.9 (s, 1H), 8.7 (d, 1H), 9.0 (s, 1H).

Source