Réaction #2461610

Équation de réaction

4-chloro-7-(3-chloropropoxy)-5-tetrahydropyran-4-yloxyquinazoline

4-amino-5-chloro-2,3-methylenedioxypyridine

→

title compound

Rendement 78.0%

4-(5-chloro-2,3-methylenedioxypyrid-4-ylamino)-7-(3-chloropropoxy)-5-tetrahydropyran-4-yloxyquinazoline

Rendement 78.0%

Conditions de réaction

Mode opératoire

Using an analogous procedure to that described in Example 1, 4-chloro-7-(3-chloropropoxy)-5-tetrahydropyran-4-yloxyquinazoline was reacted with 4-amino-5-chloro-2,3-methylenedioxypyridine to give the title compound in 78% yield; Mass Spectrum: M+H+ 493 and 495.

Source