Réaction #2383791

Équation de réaction

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine

→

4-Methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-ylamine

Solvants

methanol

Pd-C

Conditions de réaction

Traitement

1. 1
   FiltrationAfter 1 h the mixture was filtered through glass
2. 2
   Autreevaporated to an oil which

Mode opératoire

4-Methyl-7-nitro-2,3,4,5-tetrahydro-1,4-benzoxazepine (1.52 g, 6.0 mmol) was dissolved in methanol (100 ml) and hydrogenated at 50 psi in the presence of a catalytic quantity of 10% Pd-C. After 1 h the mixture was filtered through glass and evaporated to an oil which was used immediately in the next step.

Source