Réaction #2383764

ord-dfd5ee8d4f8142afabf7ec74d7a7bb2d

Équation de réaction

Cc1n[nH]cc1Cl
4-chloro-3-methylpyrazole
C=O
formalin
Cc1nn(CO)cc1Cl
solid
Rendement 95.0%
Cc1nn(CO)cc1Cl
N-hydroxymethyl-4-chloro-3-methylpyrazole
Rendement 95.0%

Réactifs

Aucun

Solvants

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreWater and methanol were then evaporated

Mode opératoire

116 g (1.0 mol) of 4-chloro-3-methylpyrazole in 50 ml of methanol were dissolved in 100 g (1.0 mol) of formalin solution (30%) at room temperature. Water and methanol were then evaporated. The title compound remained as a white solid (yield 95%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06488734B1uspto-grants-2002_12