Réaction #2320111

ord-f9aec33f77d543dca7f6a8dc6e47c7b7

Équation de réaction

FC(F)(F)c1cc(Br)ccc1Cl
5-bromo-2-chlorobenzotrifluoride
C1CNCCN1
piperazine
FC(F)(F)c1cc(N2CCNCC2)ccc1Cl
title compound
Rendement 78.2%
FC(F)(F)c1cc(N2CCNCC2)ccc1Cl
1-(4-Chloro-3-trifluoromethyl-phenyl)-piperazine
Rendement 78.2%

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Beginning with 5-bromo-2-chlorobenzotrifluoride (602 mg) and piperazine (1 g), 480 mg of the title compound was recovered by the procedure described in Example 1.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: USRE041315E1uspto-grants-2010_05