Réaction #2320110

ord-bcf1280cb0754c7fb563a0e18a80ea2f

Équation de réaction

FC(F)(F)c1cc(Cl)cc(Cl)c1
3,5-dichlorobenzotrifluoride
C1CNCCN1
piperazine
FC(F)(F)c1cc(Cl)cc(N2CCNCC2)c1
title compound
Rendement 52.1%
FC(F)(F)c1cc(Cl)cc(N2CCNCC2)c1
1-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine
Rendement 52.1%

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Beginning with 3,5-dichlorobenzotrifluoride (500 mg, 2.32 mmol) and piperazine (1 g, 11.6 mmol), 320 mg of the title compound was recovered by the procedure described in Example 1.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: USRE041315E1uspto-grants-2010_05