Réaction #2315549

Équation de réaction

4-phenylmethylbenzenesulfonic acid

triphenylsulfonium chloride

→

triphenylsulfonium 4-phenylmethylbenzenesulfonate

Rendement 52.0%

Solvants

dichloromethane

Conditions de réaction

Traitement

1. 1
   AutreThe organic layer was separated
2. 2
   Lavagewashed with 100 g of water
3. 3
   Autreevaporated in vacuum
4. 4
   AutreThe residue, 27 g, was purified by silica gel column chromatography (eluent, dichloromethane/methanol)

Mode opératoire

The 4-phenylmethylbenzenesulfonic acid crude product obtained in Synthesis Example 1 was added to the aqueous triphenylsulfonium chloride solution obtained in Synthesis Example 2 and 90 g of dichloromethane, which was stirred for one hour at room temperature. The organic layer was separated, washed with 100 g of water, and evaporated in vacuum. The residue, 27 g, was purified by silica gel column chromatography (eluent, dichloromethane/methanol), obtaining the end product, triphenylsulfonium 4-phenylmethylbenzenesulfonate. It was 21 g (yield 52%) of an oily matter containing a minor amount of solvents (methanol, etc.).

Source