Réaction #2275734

Équation de réaction

N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide

3-(4-oxo-cyclohexyl)-3H-pyrimidin-4-one

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title compounds

N-({1-[4-(6-Oxo-6H-pyrimidin-1-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide

Conditions de réaction

Mode opératoire

The title compounds were prepared as white solids from the reductive amination of 3-(4-oxo-cyclohexyl)-3H-pyrimidin-4-one (as prepared in the previous step) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in Example 2 Step C) using the procedure described in Step D of Example 1.

Source