Réaction #2200590

ord-7a3e402a4a8b4604936da49f3e7c46ea

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07432100B2uspto-grants-2008_10