Réaction #2175437

Équation de réaction

glycine

glycine

phthalic anhydride

compound b

phthalic anhydride

phthalic anhydride

→

compound 1

2-(1,3-dioxoisoindolin-2-yl)acetic acid

Conditions de réaction

Traitement

1. 1
   Autrethe co-condensation reaction

Mode opératoire

In the present invention, the (G1) step is a step to produce 2-(1,3-dioxoisoindolin-2-yl)acetic acid (compound 1) by irradiating a reaction product of glycine (compound a) and phthalic anhydride (compound b) with microwaves. In this step, glycine and phthalic anhydride undergo the co-condensation reaction to produce the compound 1. Here, water is added in a small amount to prevent overheating, so that the compound 1 to be produced is not be burned.

Source